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Prediction of thermodynamic parameters (free energy, enthalpy, entropy, and melting temperature) for 2’OMeRNA/RNA duplexes:
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Duplex:
Results:
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Important:
1/ use A, C, G and U for 2’-O-methylnucleotides and D for nucleotide
of 2,6-diaminopurine-2’-O-methylriboside. Do not use space, tabs and other
characters,
2/ 2’OMeRNA means 2’-O-methyl oligoribonucleotide whereas RNA
means oligoribonucleotide,
3/ Thermodynamic parameters are calculated for 10-4M oligomer concentration,
4/ RNA strand is added automatically,
5/ References.
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