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Publications of RNA Chemistry Laboratory

1 W.Z. Antkowiak, E. Biala, P. Dembek, R. Kierzek, K. Grzeskowiak, A. Kraszewski, M. Wiewiorowski, Further studies on synthesis and properties of the protected triester nucleotides as a new key intermediate for the synthesis of oligoribonucleotides. Nucleic Acids Res., spec. publ. No 1, 133-136 (1975)
2 R.W. Adamiak, M.Z. Barciszewska, E. Biala, K. Grzeskowiak, R. Kierzek, A. Kraszewski, W. T. Markiewicz, M. Wiewiorowski, Nucleoside 3'-phosphotriesters as key intermediates for the oligonucleotide synthesis. An improved preparation of nucleoside 3'-phosphotriesters, their 1H NMR characterization and new condition for removal of 2-cyanoethyl group. Nucleic Acids Res., 3, 3397-3408 (1976)
3 R.W. Adamiak, E. Biala, K. Grzeskowiak, R. Kierzek, A. Kraszewski, W.T. Markiewicz, J. Stawinski, M. Wiewiorowski, Nucleoside 3'-phosphotriesters as key intermediates for the oligoribonucleotide synthesis. IV. New method for removal of 2,2,2-trichloroethyl group and 31P NMR as a new tool for analysis of deblocking of internucleotide phosphate protecting groups. Nucleic Acids Res., 4, 2321-2329 (1977)
4 R.W. Adamiak, E. Biala, K. Grzeskowiak, R. Kierzek, A. Kraszewski, W.T. Markiewicz, J. Okupniak, J. Stawinski, M. Wiewiorowski, The chemical synthesis of the anticodon loop of an eukaryotic initiator tRNA containing the hypermodified nucleoside N-(N-threonylcarbonyl)adenosine. Nucleic Acids Res., 5, 1889-1905 (1978)
5 R.W. Adamiak, E. Biala, K. Grzeskowiak, R. Kierzek, A. Kraszewski, W.T. Markiewicz, J. Stawinski, M. Wiewiorowski, Studies on polynucleotide synthesis. in: Phosphorus Chemistry directed towards Biology, ed. W.J.Stec, Pergamon Press, Oxford New York, 9-12 (1980)
6 E. Biala, A.S. Jones, R.T. Walker, Synthesis and properties of poly(5-ethynyluridylic acid). Tetrahedron, 36,155-164 (1980)
7 W.T. Markiewicz, R.W. Adamiak, E. Biala, K.Grzeskowiak, R. Kierzek, A.Kraszewski, J.Stawinski, M.Wiewiorowski, Further studies on oligoribonucleotide synthesis. Nucleic Acids Res., symp. ser., 7, 115-127 (1980)
8 R. Kierzek, H. Ito, R. Bhatt, K. Itakura, Selective N-deacylation of N,O-protected nucleosides by zinc bromide. Tetrahedron Lett., 22, 3761-3764 (1981)
9 J.J. Rossi, R. Kierzek, T.Huang, P.A.Valker, K.Itakura, An alternate method for synthesis of double stranded DNA segments. J.Biol.Chem., 257, 9226-9229 (1982)
10 J.J. Rossi, R. Kierzek, T. Huang, P.A. Valker, K. Itakura, The role of synthesis of DNA in the preparation of structural genes coding for proteins. "From Gene to Protein: Translation into Biotechnology", Academic Press Inc., p. 213-219 (1982)
11 A.B. Legocki, A. Konieczny, C. Madrzak, P. Strozycki, A. Wolanski, R. Kierzek, Nodule specific induction of host genes in yellow lupin. Structure and function of plant genomes. O.Ciferii and Leon Dure III Eds., Plenum Press, New York, London, p. 263-267 (1983)
12 W.T. Markiewicz, E. Biala, R. Kierzek, Application of the tetraisopropyldisiloxane-1,3-diyl group in the chemical synthesis of oligoribonucleotides. Bull. Acad. Polon. Sci., ser. chim., 32, 433-451 (1984)
13 R.W. Adamiak, E. Biala, Scale-up procedure for the total deprotection and purification of the chemically synthesized oligoribonucleotides. Nucleic Acids Res. Symp.Ser., 14, 305-309 (1984)
14 R. Kierzek, The synthesis of 5'-O-dimethoxytrity- N-acyl-2'-deoxynucleosides. Improved transient protection approach. Nucleosides and Nucleotides, 5, 641-649 (1985)
15 R.W. Adamiak, E. Biala, B. Skalski, New ionic side-products in oligonucleotide synthesis: formation and reactivity of fluorescent N-(purin-6-yl) pyridinium salts. Nucleic Acids Res., 13, 2989-3003 (1985)
16 R.W. Adamiak, E. Biala, B. Skalski, Synthesis of 6-substituted purines and ribonucleosides with N-(6-purinyl) pyridinium Salts. Angew. Chem. Int. Ed. Engl., 24, 1054-1055 (1985)
17 R.W. Adamiak, E. Biala, Z. Gdaniec, S. Mielewczyk, B. Skalski, Reactions of nucleoside heteroaromatic lactam systems with 4-chlorophenylphosphorodichloridate and 1,2,4-triazole in pyridine. Chemica Scripta 26, 3-6 (1986)
18 R.W. Adamiak, E. Biala, Z. Gdaniec, S. Mielewczyk, B. Skalski, New observation on nucleophile assisted phosphorylation of nucleoside heteroaromatic lactam sysytem during oligonucleotide synthesis. Formation and reactivity of ionic side products. Chemica Scripta, 26, 7-10 (1986)
19 R. Kierzek, D.W. Kopp, M. Edmonds, M.H. Caruthers, Chemical synthesis of branched RNA. Nucleic Acids Res. 14, 4751-4764 (1986)
20 S.M. Freier, R. Kierzek, M.H. Caruthers, T. Neilson, D.H. Turner, Free energy contributions of G:U and other terminal mismatches to helix stability. Biochemistry 25, 3209-3213 (1986)
21 S.M. Freier, R. Kierzek, J.A. Jaeger, N. Sugimoto, M.H. Caruthers, T. Neilson, D.H. Turner, Improved free energy parameters for predictions of RNA duplex stability. Proc. Natl. Acad. Sci. USA, 83, 9373-9377 (1986)
22 D.H. Turner, S.M. Freier, N. Sugimoto, D.R. Hickey, J.A. Jaeger, A. Sinclair, D. Alkema, T. Neilson, M.H. Caruthers, R. Kierzek, Improved parameters for prediction of RNA secondary structure and insights into why RNA forms doubles helixes. 3D Structure and dynamics of RNA /P.H. van Knippenberg, C.W. Hilbers, Bosch Eds/ Plenum New York, p 1-13 (1986)
23 N. Sugimoto, R. Kierzek, S.M. Freier, D.H. Turner, Energetics of internal GU mismatches in ribooligonucleotide helixes. Biochemistry 25, 5755-5759 (1986)
24 S.M. Freier, N. Sugimoto, A. Sinclair, D. Alkema, T. Neilson, R. Kierzek, M.H. Caruthers, D.H. Turner, Stability of XGCGCp, GCGCYp, and XGCGCYp helixes: An empirical estimate of the energetics of hydrogen bonds in nucleic acids. Biochemistry 25, 3214-3219 (1986)
25 R. Kierzek, M.H. Caruthers, C.E. Longfellow, D. Swinton, D.H. Turner, S.M. Freier, Polymer supported RNA synthesis and its application to test the nearest neighbor model for duplex stability. Biochemistry 25, 7840-7846 (1986)
26 M.H. Caruthers, D. Dellinger, K. Prosser, A.D. Barone, J.W. Dubendorff, R. Kierzek, M. Rosendahl, Nucleic acid synthesis and applications to molecular biology. Chemica Scripta 26, 25-30 (1986)
27 L.J. McBride, R. Kierzek, S.L. Beaucage, M.H. Caruthers, Amidine protecting groups for oligonucleotide synthesis. J. Am. Chem. Soc., 108, 2040-2048 (1986)
28 R.W. Adamiak, E. Biala, Z. Gdaniec, S. Mielewczyk, B. Skalski, Studies directed toward introduction of N6-isopenthenyladenosine and its 2-methyl- thio- analogs into oligoribonucleotides. Nucleic Acids Res. Symp. Ser.,18, 105-109 (1987)
29 R. Kierzek, M. Rozek, W.T. Markiewicz, Some steric aspects of synthesis of oligoribonucleotides by phosphoramidite approach on solid support. Nucleic Acids Res., symp. ser., 18, 201-205 (1987)
30 W.T. Markiewicz, R. Kierzek, B. Hernes, A new method of synthesis of 4N-alkyl substituted cytosine derivatives via 4N-arylsulfonyl or alkylsulfonyl intermediates. Nucleosides and Nucleotides, 6, 269-273 (1987)
31 R. Kierzek, W.T. Markiewicz, Synthesis of 5'-0-dimethoxytrityl-4-N-(6-trifluoroacetamidohexyl) 2'-deoxycytidine and its application in the synthesis of biotin labelled oligonucleotides. Nucleosides and Nucleotides, 6, 463-466 (1987)
32 R. Kierzek, W.T. Markiewicz, B. Imiolczyk, Synthesis of 2' 5' oligonucleotides on solid support by phosphoramidite method. "Biophosphates and their Analogues Synthesis, Structure, Metabolism and Activity", eds. K.S. Bruzik, W.J. Stec, Elsevier Sci.Publ., 179-184 (1987)
33 D.H. Turner, N. Sugimoto, R. Kierzek, S.D. Dreiker, Free energy increments for hydrogen bonds in nucleic acid base pairs. J. Am. Chem. Soc., 109, 3783-3785 (1987)
34 N. Sugimoto, R. Kierzek, D.H. Turner, Sequence dependence for the energetics of dangling ends and terminal base pairs in ribonucleic acid. Biochemistry, 26, 4554-4559 (1987)
35 N. Sugimoto, R. Kierzek, D.H. Turner, Sequence dependence for the energetics of terminal mismatches in ribooligonucleotides. Biochemistry, 26, 4559-4562 (1987)
36 D.H. Turner, N. Sugimoto, J.A. Jaeger, C.E. Longfellow, S.M. Freier, R. Kierzek, Improved parameters for prediction of RNA structure. Cold Spring Harbor Symposia on Quantitative Biology, vol. LII, 123-133, (1987)
37 M.H. Caruthers, R. Kierzek, J.Y. Tang, Synthesis of oligonucleotides using the phosphoramidite method. "Biophosphates and their Analogues Synthesis, Structure, Metabolism and Activity", eds. K.S. Bruzik, W.J. Stec, Elsevier Sci. Publ., 3-21 (1987)
38 R. Kierzek, M. Rozek, W.T. Markiewicz, Some steric aspect of synthesis of oligoribonucleotides by phosphoramidite approach on a solid support. Bull. Pol. Ac.: Chem., 35 (11 12), 508-517 (1987)
39 D.H. Turner, N. Sugimoto, S.D. Dreiker, S.M. Freier, R. Kierzek, Hydrogen bonding and stacking contributions to nucleic acid stability. Proteins to Ribosomes, Adenine Press p. 249-259 (1988)
40 N. Sugimoto, R. Kierzek, D.H. Turner, Kinetics for reaction of a circularized intervening sequence with CU, UCU, CUCU, and CUCUCU: mechanistic implications from the dependence on temperature, and on oligomer and Mg+2 concentrations Biochemistry, 27, 6384-6392 (1988)
41 N. Sugimoto, M. Tomka, R. Kierzek, P. Bevilacqua, D.H. Turner, Effects of substrate structure on the kinetics of circle opening reactions of the self splicing intervening sequence from Tetrahymena thermophila: evidence for substrate and Mg+2 binding interactions Nucleic Acids Res., 17, 355-371 (1989)
42 A.P. Williams, C.E. Longfellow, S.M.Freier, R. Kierzek, D.H. Turner, Laser temperature jump, spectroscopic and thermodynamic study of salt effects on duplex formation by dGCATGC. Biochemistry, 28, 4283-4291 (1989)
43 N. Sugimoto, N. Sasaki, R. Kierzek , D.H. Turner, Binding of a fluorescent oligonucleotide to a circularized intervening sequence from Tetrahymena thermophila. Chem. Lett., 2223-2226 (1989)
44 M. Welnicki, J. Skrzeczkowski, A. Soltynska, P. Jonczyk, W.T. Markiewicz, R. Kierzek, B. Imiolczyk, W. Zagorski, Characterization of synthetic DNA probe detecting potato spindle tuber virioid. J. Virological Methods, 24, 141-152 (1989)
45 R. Kierzek, W.T. Markiewicz, A general method of synthesis of 5'-O-dimethoxytrityl 3'-O-tetrahydropyranyl-N-acylribonucleosides. Bull. Pol. Ac.:Chem., 38, 33-40 (1990)
46 C.E. Longfellow, R. Kierzek , D.H. Turner, Thermodynamic and spectroscopic study of bulge loops in oligoribonucleotides. Biochemistry, 29, 278-285 (1990)
47 J. SantaLucia Jr., R. Kierzek, D.H. Turner, Effects of G-A mismatches on the structure and thermodynamics of RNA internal loops. Biochemistry, 29, 8813-8819 (1990)
48 J.D. Reilly, S.K. Freeman, R.F. Melhan, R. Kierzek, M.H. Caruthers, M. Edmonds T.W. Munns, Antibodies specific for branched oligoribonucleotides. Anal. Biochem., 185, 125-130 (1990)
49 N. Sugimoto, M. Sasaki, R. Kierzek , D.H. Turner, Inhibition of deoxyribooligonucleotides on the circle opening of the intervening sequence from Tetrahymena thermophila. Chem. Lett., 747-748 (1990)
50 G. Slim, C. Pritchard, E. Biala, U. Asseline, M. Gait, Synthesis of site-specifically modified ologoribonucleotides for studies of the recognition of TAR RNA by HIV-1 tat protein and studies on hammerhead ribozymes. Nucleic Acids Res. Symp. Ser., 24, 55-59 (1991)
51 J. SantaLucia Jr., R. Kierzek , D.H. Turner, Functional group substitutions as probes of hydrogen bonding between G A mismatches in RNA internal loops. J. Am. Chem. Soc., 113, 4313-4322 (1991)
52 A. Peritz, R. Kierzek, N. Sugimoto, D.H. Turner, Thermodynamic study of internal loops in oligoribonucleotides: symmetric loops are more stable than asymmetric loops. Biochemistry, 30, 6428-6436 (1991)
53 J. SantaLucia Jr., R. Kierzek, D.H. Turner, Stabilities of consecutive A-C, C-C, G-G, U-C and U-U mismatches in RNA internal loops: evidence for stable hydrogen bonded U-U and C-C+ pairs. Biochemistry, 30, 8242-8251 (1991)
54 L. He, R. Kierzek, J. SantaLucia Jr., A.E.Walter, D.H. Turner, Nearest neighbor parameters for G U mismatches: 5'GU 3'/3'UG 5' is destabilizing in the contexts CGUG/GUGC, UGUA/AUGU and AGUU/UUGA but stabilizing in GGUC/CUGG. Biochemistry, 30, 11124-11132 (1991)
55 R. Kierzek, W.T. Markiewicz, The synthesis of 5'-O-triphosphate 4-N-(omega-aminoalkyl)deoxycytidine, a useful precursor to the generation of different labeled triphosphates. Nucleosides and Nucleotides, 10, 1257-1275 (1991)
56 J. SantaLucia Jr., R. Kierzek, D.H. Turner, Context dependence of hydrogen bond free energy revealed by substitutions in an RNA hairpin. Science, 256, 217-219 (1992)
57 R. Kierzek, L. He, D.H. Turner, Association of 2'-5' oligoribonucleotides. Nucleic Acids Res., 20, 1685-1690 (1992)
58 R. Kierzek, Nonenzymatic hydrolysis of oligoribonucleotides. Nucleic Acids Res., 20, 5079-5084 (1992)
59 R. Kierzek, Hydrolysis of oligoribonucleotides: influence of sequence and length. Nucleic Acids Res., 20, 5073-5077 (1992)
60 P.C. Bevilacqua, R. Kierzek, K.A. Johnson, D.H. Turner, Dynamics of ribozyme binding of substrate revealed by fluorescence detected stopped flow. Science, 258, 1355-1358 (1992)
61 R. Kierzek, Y. Li, D.H. Turner, P.C. Bevilacqua, 5'-Amino pyrene provides a sensitive, non perturbing fluorescent probe of RNA secondary and tertiary structure formation. J. Am. Chem. Soc., 115, 4985-4992 (1993)
62 E. Biala, J. Milecki, A. Kowalewski, M. Popenda, W.Z. Antkowiak, Z-RNA. The synthesis of 5-methyl and 2`-O-methyl analogs of ribo-CGCGCG. Acta Biochim. Pol., 40, 521-529 (1993)
63 S. Moran, R. Kierzek, D.H. Turner, Binding of guanosine and 3'-splice site analogues to a group I ribozyme: interactions with functional groups of guanosine and additional nucleotides. Biochemistry, 32, 5247-5257 (1993)
64 M. Culver, S.M. McCraith, M. Zillmann, R. Kierzek, N. Michaud. R.D. LaReau. D.H. Turner , E.M. Phizicky, A novel NAD derivative produced during transfer RNA splicing: ADP-ribose 1''-2'' cyclic phosphate. Science, 261, 266-208 (1993)
65 R. Kierzek, The stability of trisubstituted internucleotide bond in the presence of vicinal 2'-hydroxyl. Chemical synthesis of the uridyl-(2'-phosphate)-3'-5'-uridine. Nucleotides and Nucleosides, 13, 1757-1768 (1994)
66 W.B.T. Cruse, P. Saludjian, E. Biala P. Strazewski, T. Prange, O. Kennard, Structure of a mispaired RNA double helix at 1.6 A resolution and implication for the prediction of RNA secondary structure. Proc. Natl. Acad. Sci. USA., 91, 4160-4165 (1994)
67 M. Popenda, J. Milecki, E. Biala, R.W. Adamiak, The solutions of NMR structure of 2`-O-(13C)methyl-CGCGCG RNA duplex. Nucleosides & Nucleotides, 14, 983-988 (1995)
68 A. Burdzy, B. Skalski, E. Biala, A. Kowalewski, S. Paszyc, R.W. Adamiak, Post-synthetic transformations of oligodeoxynucleotides originated at 6-methylthio-purine site. Nucleosides & Nucleotides, 14, 978-982 (1995)
69 R. Kierzek, Wlasciwosci katalityczne kwasów rybonukleinowych (RNA) (The catalytic properties of ribonucleic acids) "Nowe tendencje w biologii molekularnej i inzynierii genetycznej" (The new trends, in molecular biology and genetic engineering), (J. Barciszewski, K. Lastowski, T. Twardowski, Editors), Sorus, Poznan, p. 137-185 (1996)
70 A. Fischer, Z. Gdaniec, E. Biala, M. Lozynski, J. Milecki, R.W. Adamiak, 19F NMR of RNA. The structural and chemical aspects of 5-fluorocytidine and -uridine labelling of oligoribonucleotides. Nucleosides & Nucleotides 15, 477-488 (1996)
71 R. Kierzek, The effect of support and mobile phase on diastereoisomers separation of monophosphate of DNA and RNA oligomers by high performance liquid chromatography. Collect. Czech. Chem. Commun., 61, 161-163 (1996)
72 R. Kierzek, Nonenzymatic hydrolysis of oligoribonucleotides III. Stereochemistry and influence of chimeric DNA/RNA on nonenzymatic hydrolysis of oligoribonucleotides. Collect. Czech. Chem. Commun., 61, 253-257 (1996)
73 L. Profenno, R. Kierzek, S. Testa, D. Turner, Guanosine binds to the tetrahymena ribozyme in more than one step, and its 2'-OH and the nonbridging pro-Sp-phsphoryl oxygen at the cleavage site are required for productive docking Biochemistry, 36, 12477-12485 (1997)
74 M. Popenda, E. Biala, J. Milecki, R.W. Adamiak, Solution structure of RNA duplexes containing alternating CG base pairs: NMR study of r(CGCGCG)2 and 2`-O-Me(CGCGCG)2 under low salt conditions. Nucleic Acids Res., 25, 4589-4598 (1997)
75 T. Xia, J. SantaLucia, M.E. Burkard, R. Kierzek, S.J. Schroeder, C. Cox and D.H. Turner, Parameters for expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pair. Biochemistry, 37, 14719-14735 (1998)
76 S. Gunzenhauser, E. Biala, P. Strazewski, Tetraethylene glycol-derived spacer for oligonucleotide synthesis. Tetrahedron Lett., 39, 6277-6280 (1998)
77 R. Kierzek, Wlasciwosci termodynamiczne kwasow rybonukleinowych., "Na pograniczu chemii i biologii", H. Koroniak, J. Barciszewski, W.T. Markiewicz, K. Ziemnicki (eds), Wydawnictwo Naukowe UAM, p. 369-416 (1998)
78 S.L. Spinelli, R. Kierzek. D.H. Turner, E.M. Phizicky, Transient ADP-ribosylation of a 2'-phosphate implicated in its removal from ligated tRNA during splicing in yeast. J. Biol. Chem., 274, 2637-2644 (1999)
79 E. Biala, P.Strazewski, Thermodynamics of site-specific variant tRNAAla acceptor stem microharpins. Nucleosides & Nucleotides, 18, 1575-1576 (1999)
80 P. Strazewski, E. Biala, K.Gabriel, W.H. McClain, The relationship of thermodynamic stability at a GU recognition site to tRNA aminoacylation specifity. RNA, 5, 1490-1494 (1999)
81 E. Biala, O. Botta, E. Moyroud, P.Strazewski, Ribonucleosides, aminoacyl- and peptidyl-RNA: synthesis, thermodynamics and structure. Chimia, 53, 226-227 (1999)
82 A. Bibillo, K. Ziomek, M. Figlerowicz, R. Kierzek, Nonenzymatic hydrolysis of oligoribonucleotides V. The elements affecting the process of self-hydrolysis. Acta Biochemica Polonica, 46, 145-153 (1999)
83 A. Bibillo, M. Figlerowicz, R. Kierzek, The nonenzymatic hydrolysis of oligoribonucleotides VI. The role of biogenic polyamines. Nucleic Acids Res., 27, 3931-3937 (1999)
84 M.E. Burkard, R. Kierzek, D.H. Turner, Thermodynamics of unpaired terminal nucleotides on short RNA helixes correlates with stacking at helix termini in larger RNAs. J. Mol. Biol., 290, 967-982 (1999)
85 R. Kierzek, M.E. Burkard, D.H. Turner, The thermodynamics of single mismatches in RNA duplxes Biochemistry, 38, 14214-14223 (1999)
86 S.M. Testa, M.D. Disney, D.H. Turner, R. Kierzek, Thermodynamics of RNA-RNA duplexes with 2- and 4-thiouridenes: implications for antisense design and targeting a group I intron. Biochemistry, 38, 16655-16662 (1999)
87 K. Ziomek, R. Kierzek, Przewidywanie struktur drugorzedowych kwasow rybonukleinowych (RNA) metoda termodynamiczna. Postepy Biochemii, 45, 74-80 (1999)
88 K.Ziomek, R. Kierzek, Drugorzedowe motywy strukturalne RNA. Postepy Biochemii, 45, 80-87 (1999)
89 E. Moyroud, E. Biala, P. Strazewski, Synthesis and enzymatic digestion of an RNA nonamer in both enantiomeric forms. Tetrahedron, 56, 1475-1484 (2000)
90 R. Kierzek, M.A. Steiger, S.L. Spinelli, D.H. Turner, E.M. Phizicky, The chemical synthesis of oligoribonucleotides with selectively placed 2'-O-phosphates. Nucleosides, Nucleotides & Nucleic Acids, 19, 917-933 (2000)
91 A. Bibillo, M. Figlerowicz, K. Ziomek, R. Kierzek, The nonenzymatic hydrolysis of oligoribonucleotides VII. Structural elements affecting hydrolysis. Nucleosides, Nucleotides & Nucleic Acids, 19, 977-994 (2000)
92 X. Chen, J.A. McDowell, R. Kierzek, T.R. Krugh, and D.H. Turner, Nuclear magnetic resonance spectroscopy and molecular modeling reveal that different hydrogen bonding patterns are possible for G-U pairs: one hydrogen bond for each G-U pair in r(GGCGUGCC)2 and two for each G-U pair in r(GAGUGCUC)2. Biochemistry, 39, 8970-8982 (2000)
93 X. Chen, R. Kierzek and D.H. Turner, Stability and Structure of RNA Duplexes containing Isoguanosine and Isocytidine. J. Am. Che. Soc., 123, 1267-1274 (2001)
94 E. Kierzek, R. Kierzek, Influence of N6-isopentenyladenosine (i6A) on thermal stability of RNA duplexes. Biophysical Chemistry, 91, 135-140 (2001)
95 R. Kierzek, Nonenzymatic cleavage of oligoribonucleotides. Methods in Enzymology, vol 341A, p. 657-675, Ed. A.W. Nicholson, Academic Press, San Diego, London, Boston, New York, Sydney, Tokyo, Toronto (2001)
96 M. Alejska, A. Kurzynska-Kokorniak, M. Broda, R. Kierzek and M. Figlerowicz, How RNA viruses exchange their genetic material. Acta Biochimica Polonica, 48, 391-407 (2001).
97 E. Kierzek, E. Biala and R. Kierzek, Elements of thermodynamics in RNA evolution. Acta Biochemica Polonica, 48, 485-493 (2001)
98 K. Ziomek, E. Kierzek, E. Biala and R. Kierzek, The thermal stability of RNA duplexes containing modified base pairs placed at internal and terminal positions of the oligoribonucleotides. Biophysical Chemistry, 97, 233-241 (2002)
99 K. Ziomek, E. Kierzek, E. Biala and R. Kierzek, The influence of various modified nucleotides placed as 3'-dangling end on thermal stability of RNA duplexes. Biophysical Chemistry, 97, 243-249 (2002)
100 D.E. Proctor, E. Kierzek, R. Kierzek and P.C. Bevilacqua, Restricting the conformational heterogeneity of RNA by specific incorporation of 8-bromoguanosine. J. Am. Chem. Soc., 125, 2390-2391 (2003)
101 E. Kierzek and R. Kierzek, The synthesis of oligoribonucleotides containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines via post-synthetic modifications of precursor oligomers. Nucleic Acids Research, 31, 4461-4471 (2003)
102 E. Kierzek and R. Kierzek, The thermodynamic stability of RNA duplexes and hairpins containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines Nucleic Acids Research, 31, 4472-4480 (2003)
103 S. Terenzi S. E. Biala E. N,Q. Nguyen-Trung and P. Strazewski, Amphiphilic 3'-peptydyl-RNA conjugates Angewandte Chemie Internat. Edition, 42, 2909-2912 (2003)
104 E. Kierzek, R. Kierzek, The synthesis of oligoribonucleotides containing N6-alkyladenosines and 2-methylthio-N6-alkyladenosines. Current Protocols in Nucleic Acids Chemistry 4.23.1-4.23.21 John Wiley & Sons, Inc (2004)
105 R. Kierzek, Structural considerations for the spontaneous cleavage of RNA. Proceeding in Nucleic Acids and Molecular Biology, Vol. 13, p. 33-48, Artificial nucleases, M.A. Zenkova (Ed.), Springer-Verlag, Berlin Heidelberg (2004)
106 J. Proctor, H. Ma, E. Kierzek, R. Kierzek, M. Gruebele, and P. C. Bevilacqua, Folding Thermodynamics and Kinetics of YNMG RNA Hairpins: Specific Incorporation of 8-Bromoguanosine Leads to Stabilization by Enhancement of the Folding Rate. Biochemistry, 43, 14004-14014 (2004)
107 M. Lewdorowicz, Y.Yoffe, J. Zuberek, J. Jemielity, J. Stepinski, R. Kierzek, R. Stolarski, M. Shapira and E. Darzynkiewicz, Chemical synthesis and binding activity of trypanosomatid cap-4 structure RNA, 10, 1469-1478 (2004)
108 M. Broda, R. Kierzek, Mutacje dynamiczne trojnukleotydowych powtorzen DNA w genomie czlowieka oraz ich zwiazek z chorobami neurologicznymi. redaktorzy - H.Koroniak, J.Barciszewsk (eds), "Na pograniczu biologii i chemii", Wydawnictwo Naukowe UAM, p. 51-95 (2004)
109 E. Kierzek, A. Ciesielska, K. Pasternak, D.H. Mathews, D.H. Turner and R. Kierzek, The influence of locked nucleic acid residues on thermodynamic properties of 2'-O-methyl RNA/RNA hetroduplexes. Nucleic Acids Research, 33, 5082-5093 (2005)
110 P. Kedziora, M. Figlerowicz, P. Formanowicz, M. Alejska, P. Jackowiak, N. Malinowska, A. Fratczak, J. Blazewicz, M. Figlerowicz, Computational methods in diagnostics of chronic hepatitis C. Bulletin of the Polish Academy of Sciences; Technical Sciences, 53, 273-281 (2005)
111 M. Broda, E. Kierzek, Z. Gdaniec, T. Kulinski and R. Kierzek, Thermodynamic stability of RNA structures formed by CNG trinucleotide repeats. Implication for prediction of RNA structure. Biochemistry, 44, 10873-10882 (2005)
112 M. Lewdorowicz, J. Jemielity, R. Kierzek, M. Shapira, J. Stepinski, R. Stolarski, and E. Darzynkiewicz, Solid-support synthesis of 5' mRNA CAP-4 from trypanosomatides. Collection symposium Series, 7, 433-435 (2005)
113 E. Kierzek, R. Kierzek, D. H. Turner and I. E. Catrina, Facilitating RNA Structure Prediction with Microarrays, Biochemistry, 45, 581-593 (2006)
114 H. Ma, D.J. Proctor, E. Kierzek, R. Kierzek, P.C. Bevilacqua and M. Gruebele, Exploring the Energy landscape of a small RNA hairpin. J. Am. Chem. Soc., 128, 1523-1530 (2006)
115 E. Kierzek, D.H. Mathews, A. Ciesielska, D.H. Turner and R. Kierzek, Nearest neighbor parameters for Watson-Crick complementary heteroduplex formed between 2'-O-methyl RNA and RNA oligonucleotides. Nucleic Acids Research, 34, 3609-3614 (2006)
116 R. Yajima, D.J. Proctor, R. Kierzek, E. Kierzek, P. C. Bevilacqua, A conformationally restricted guanosine analogue reveals the catalytic relevance of three structures of an RNA enzyme. Chemistry and Biology, 14, 23-30 (2007)
117 A. Pasternak, E. Kierzek, K. Pasternak, D. H. Turner and R. Kierzek, A chemical synthesis of LNA-2,6-diaminopurine riboside, and the influence of 2'-O-methyl-2,6-diaminopurine and LNA-2,6-diaminopurine ribosides on the thermodynamic properties of 2'-O-methyl RNA/RNA heteroduplexes. Nucleic Acids Research, 35, 4055-4063, (2007)
118 C. Gang, R. Kierzek, I. Yildirim, T. R. Krugh, D.H. Turner and S.D. Kennedy, Stacking Effects on Local Structure in RNA: The Structure of Tandem GA Pairs Changes When Flanking GC Pairs are Replaced by isoG-isoC Pairs J. Phys. Chem. B, 111, 6718-6727 (2007)
119 M. Lewdorowicz, J. Jemielity, R. Kierzek, M. Shapira, J. Stepinski, R. Stolarski, and E. Darzynkiewicz, Solid-supported synthesis of 5' mRNA CAP-4 from Trypanosomatides. Nucleosides, Nucleotides and Nucleic Acids, 26, 1329-133 (2007)
120 M. Lewdorowicz, J. Stepinski, J. Jemielity, J. Zuberek, R. Kierzek, M. Shapira, J. Stepinski and E. Darzynkiewicz, Syntheisis of 5'-mRNA CAP analogues (CAP-2 and CAP3) from Leishmana. Nucleosides, Nucleotides and Nucleic Acids, 26, 1339-1348 (2007)
121 E. Kierzek, A. Fratczak, A. Pasternak, D. H. Turner and R. Kierzek, Isoenergetic RNA microarrays, a new method to study the structure and interactions of RNA. 2nd European Conference on Chemistry for Life Sciences, Wroclaw, Medimond, International Proceedings Division, p. 25-30, Bologna, Italy (2007)
122 A. Pasternak, E. Kierzek, K. Pasternak, A. Fratczak, D.H. Turner and R. Kierzek, The thermodynamics of 3'-terminal pyrene and guanosine for the design of isoenergetic 2'-O-methyl-RNA-LNA chimeric oligonucleotide probes of RNA structure. Biochemistry, 47, 1249-1258 (2008)
123 E. Kierzek, R. Kierzek, W. Moss, S. Christensen, T. Eickbush; D.H. Turner, Isoenergetic Penta- and Hexanucleotide Microarray Probing and Chemical Mapping Provide a Secondary Structure Model for an RNA Element Orchestrating R2 Retrotransposon Protein Function. Nucleic Acids Research, 36, 1770-1782 (2008)
124 A. Pasternak, R. Kierzek, Modyfikowane nukleotydy jako narzedzia molekularne sluzace do kontrolowanej zmiany wlasciwosci fizykochemicznych RNA. Na pograniczu chemii i biologii, tom XVII, p. 41-87, Wydawnictwo UAM (2008)
125 K. Kubiak, J. Kazmierczak-Baranska, E. Sochacka, R. Kierzek, M. Janicka, K.Brzuska and B. Nawrot, Modulation of silencing activity of siRNAs by chemical modifications. Collection symposium series, 70, 264-267 (2008)
126 A. Pasternak, R. Kierzek, Z. Gdaniec and M. Gdaniec, A locked derivative of 8-aza-7-deazaadenosine Acta Crystalographica, C64, 467-470 (2008)